Vardenafil (Valif) 20mg Tablet

Vardenafil is a phosphodiesterase-5 (PDE5) inhibitor. It is an oral medication for male sexual disorders such as erectile dysfunction. This drug helps increase blood flow to the penis to achieve sustained erection. 

Vardenafil is a specific and effective enzyme inhibitor of phosphodiesterase (PDE5), responsible for cyclic guanosine monophosphate (cGMP) metabolism in the smooth muscles. PDE type 5 enzyme inhibition allows smooth muscle relaxation and increased blood flow during sexual stimulation into the penis’ corpus cavernosum, thus producing an erection.

Drug = Vardenafil

Strength = 20 mg

Manufacturer = Indian GMP

Quantity per sleeve =  10  Tablet (for the price quoted)

How To Take Vardenafil (Valif) 20mg

This medicine may be taken with or without food.

Try to take it at the same time each day. It must be taken regularly for it to be effective. 

Take exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor. Do not stop taking it unless instructed by the doctor.

Dosage of Vardenafil (Valif) 20mg

Adult: As general tab: Usual dose is 10 mg as needed; may adjust according to response (range: 5-20 mg). As orodispersible tab: Maximum dose of 10 mg as needed. The dose is taken approximately 25-60 minutes before sexual intercourse. The maximum dosing frequency is once every 24 hours.

Elderly: As conventional tab: 5 mg as needed, at least 25-60 minutes before sexual intercourse. Maximum dose of 20 mg. The maximum dosing frequency is once every 24 hours.

Missed Dose of Vardenafil (Valif) 20mg

If you often forget to take your medicine, let your doctor and pharmacist know.

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

Do not double a dose under any circumstances.

Overdose

If you think you may have used Vardenafil more than the usual dose, please seek medical help immediately.

Symptoms of overdose may include the following:

• Back pain/myalgia
• Abnormal vision

Contraindications of Vardenafil (Valif) 20mg

People with the following medical conditions should not take Vardenafil:

• Severe cardiovascular disorder or recent history of stroke or MI (within the last six months)
• Unstable angina
• Retinitis pigmentosa
• Vision loss due to non-arteritic anterior ischaemic optic neuropathy (NAION),
• End-stage renal disease requiring dialysis
• Hypotension <90/50 mmHg
• Other conditions wherein sexual intercourse is inadvisable
• Severe hepatic impairment (Child-Pugh class C)

Side Effects

Vardenafil may have the following side effects:

• Hypotension
• Color discrimination impairment
• Vision lose/NAION
• Sudden decrease or loss of hearing
• Tinnitus
• Prolonged/painful erection or priapism (rare)
• Dyspepsia
• Nausea
• Flu-like symptoms
• Headache
• Dizziness
• Nasal congestion
• Sinusitis

Warnings of Vardenafil (Valif) 20mg 

Do not take Vardenafil with the following medicines:

• Alpha-blockers 
• Ketoconazole
• Clarithromycin
• Ritonavir
• Quinidine
• Procainamide
• Amiodarone
• Sotalol
• Antiarrhythmics

Potentially Fatal:

• Organic nitrates/nitrites
• Riociguat

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicine, supplements, and medicines that you buy without a prescription.

This list does not include all medicines that may interact with Vardenafil.

How Does It Work?

Vardenafil is a potent and selective phosphodiesterase (PDE5) enzyme inhibitor responsible for the metabolism of cyclic guanosine monophosphate (cGMP) in the smooth muscles. The inhibition of PDE type 5 enzyme causes smooth muscle relaxation and increased blood flow into the corpus cavernosum of the penis during sexual stimulation, thereby producing an erection.

Uses 

Vardenafil is used to treat the following conditions:

• Erectile dysfunction

Special Precautions and Connected Warnings

Take special precautions if you have the following conditions:

• Patient with cardiovascular disease,
• Aortic stenosis
• Hypertrophic obstructive cardiomyopathy
• Anatomical penile deformation
• Sickle cell anemia
• Multiple myeloma
• Leukemia
• Bleeding disorders
• Peptic ulcer disease
• Severe renal and mild to moderate hepatic impairment
• Elderly
• Pregnancy
• Lactation

Storage Conditions

• Store at 25°C.
• Store in a cool, dry place away from the reach of children.
• Do not use Vardenafil that is expired or out of date.